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G protein‐coupled receptor 119 agonist DS‐8500a effects on pancreatic β‐cells in Japanese type 2 diabetes mellitus patients

AIMS/INTRODUCTION: Pancreatic β‐cell dysfunction contributes to type 2 diabetes mellitus progression. Drugs that improve insulin secretion might be a valuable treatment approach. The present study aimed to evaluate the effect of the G protein‐coupled receptor 119 agonist DS‐8500a on insulin secretor...

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Detalles Bibliográficos
Autores principales: Watada, Hirotaka, Shiramoto, Masanari, Irie, Shin, Terauchi, Yasuo, Yamada, Yuichiro, Shiosakai, Kazuhito, Myobatake, Yusuke, Taguchi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319480/
https://www.ncbi.nlm.nih.gov/pubmed/29624887
http://dx.doi.org/10.1111/jdi.12849