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p62‐mediated autophagy affects nutrition‐dependent insulin receptor substrate 1 dynamics in 3T3‐L1 preadipocytes

AIMS/INTRODUCTION: Previous studies have shown that an organism's nutritional status changes the protein levels of insulin receptor substrate 1 (IRS‐1) in a tissue‐specific manner. Although the mechanisms underlying the regulation of IRS‐1 in the nutrient‐rich conditions associated with diabete...

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Detalles Bibliográficos
Autores principales: Igawa, Hirobumi, Kikuchi, Akihiro, Misu, Hirofumi, Ishii, Kiyo‐aki, Kaneko, Shuichi, Takamura, Toshinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319485/
https://www.ncbi.nlm.nih.gov/pubmed/29786968
http://dx.doi.org/10.1111/jdi.12866