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Autophagy Is a Potential Target for Enhancing the Anti-Angiogenic Effect of Mebendazole in Endothelial Cells

Mebendazole (MBZ), a microtubule depolymerizing drug commonly used for the treatment of helminthic infections, has recently been noted as a repositioning candidate for angiogenesis inhibition and cancer therapy. However, the definite anti-angiogenic mechanism of MBZ remains unclear. In this study, w...

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Detalles Bibliográficos
Autores principales: Sung, So Jung, Kim, Hyun-Kyung, Hong, Yong-Kil, Joe, Young Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319545/
https://www.ncbi.nlm.nih.gov/pubmed/30642153
http://dx.doi.org/10.4062/biomolther.2018.222