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Use of Levosimendan in Intensive Care Unit Settings: An Opinion Paper
Levosimendan is an inodilator that promotes cardiac contractility primarily through calcium sensitization of cardiac troponin C and vasodilatation via opening of adenosine triphosphate–sensitive potassium (K(ATP)) channels in vascular smooth muscle cells; the drug also exerts organ-protective effect...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Cardiovascular Pharmacology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319595/ https://www.ncbi.nlm.nih.gov/pubmed/30489437 http://dx.doi.org/10.1097/FJC.0000000000000636 |