Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain

Clinical studies indicate that cannabidiol (CBD), the primary nonaddictive component of cannabis that interacts with the serotonin (5-HT)(1A) receptor, may possess analgesic and anxiolytic effects. However, its effects on 5-HT neuronal activity, as well as its impact on models of neuropathic pain ar...

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Detalles Bibliográficos
Autores principales: De Gregorio, Danilo, McLaughlin, Ryan J., Posa, Luca, Ochoa-Sanchez, Rafael, Enns, Justine, Lopez-Canul, Martha, Aboud, Matthew, Maione, Sabatino, Comai, Stefano, Gobbi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319597/
https://www.ncbi.nlm.nih.gov/pubmed/30157131
http://dx.doi.org/10.1097/j.pain.0000000000001386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319597/
https://www.ncbi.nlm.nih.gov/pubmed/30157131
http://dx.doi.org/10.1097/j.pain.0000000000001386

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