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Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program

Ectopic expression of defined transcription factors can force direct cell fate conversion from one lineage to another in the absence of cell division. Several transcription factor cocktails have enabled successful reprogramming of various somatic cell types into induced neurons (iNs) of distinct neu...

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Detalles Bibliográficos
Autores principales: Karow, Marisa, Camp, J. Gray, Falk, Sven, Gerber, Tobias, Pataskar, Abhijeet, Gac-Santel, Malgorzata, Kageyama, Jorge, Brazovskaja, Agnieska, Garding, Angela, Fan, Wenqiang, Riedemann, Therese, Casamassa, Antonella, Smiyakin, Andrej, Schichor, Christian, Götz, Magdalena, Tiwari, Vijay K., Treutlein, Barbara, Berninger, Benedikt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319609/
https://www.ncbi.nlm.nih.gov/pubmed/29915193
http://dx.doi.org/10.1038/s41593-018-0168-3