Curare alkaloids from Matis Dart Poison: Comparison with d-tubocurarine in interactions with nicotinic, 5-HT(3) serotonin and GABA(A) receptors

Several novel bisbenzylisoquinoline alkaloids (BBIQAs) have recently been isolated from a Matis tribe arrow poison and shown by two-electrode voltage-clamp to inhibit mouse muscle nicotinic acetylcholine receptors (nAChR). Here, using radioligand assay with Aplysia californica AChBP and radioiodinat...

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Detalles Bibliográficos
Autores principales: Spirova, Ekaterina N., Ivanov, Igor A., Kasheverov, Igor E., Kudryavtsev, Denis S., Shelukhina, Irina V., Garifulina, Alexandra I., Son, Lina V., Lummis, Sarah C. R., Malca-Garcia, Gonzalo R., Bussmann, Rainer W., Hennig, Lothar, Giannis, Athanassios, Tsetlin, Victor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319706/
https://www.ncbi.nlm.nih.gov/pubmed/30608952
http://dx.doi.org/10.1371/journal.pone.0210182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319706/
https://www.ncbi.nlm.nih.gov/pubmed/30608952
http://dx.doi.org/10.1371/journal.pone.0210182

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