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Spatiotemporally controlled genetic perturbation for efficient large-scale studies of cell non-autonomous effects
Studies in genetic model organisms have revealed much about the development and pathology of complex tissues. Most have focused on cell-intrinsic gene functions and mechanisms. Much less is known about how transformed, or otherwise functionally disrupted, cells interact with healthy ones toward a fa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320068/ https://www.ncbi.nlm.nih.gov/pubmed/30479273 http://dx.doi.org/10.7554/eLife.38393 |