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Spatiotemporally controlled genetic perturbation for efficient large-scale studies of cell non-autonomous effects

Studies in genetic model organisms have revealed much about the development and pathology of complex tissues. Most have focused on cell-intrinsic gene functions and mechanisms. Much less is known about how transformed, or otherwise functionally disrupted, cells interact with healthy ones toward a fa...

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Detalles Bibliográficos
Autores principales: Chai, Andrea, Mateus, Ana M, Oozeer, Fazal, Sousa-Nunes, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320068/
https://www.ncbi.nlm.nih.gov/pubmed/30479273
http://dx.doi.org/10.7554/eLife.38393