Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine

Mutations in SPINT2 encoding the epithelial serine protease inhibitor hepatocyte growth factor activator inhibitor-2 (HAI-2) are associated with congenital tufting enteropathy. However, the functions of HAI-2 in vivo are poorly understood. Here we used tamoxifen-induced Cre-LoxP recombination in mic...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Makiko, Yamamoto, Koji, Takeda, Naoki, Fukushima, Tsuyoshi, Yamashita, Fumiki, Sato, Katsuaki, Kitamura, Kenichiro, Hippo, Yoshitaka, Janetka, James W., Kataoka, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320337/
https://www.ncbi.nlm.nih.gov/pubmed/30623107
http://dx.doi.org/10.1038/s42003-018-0255-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320337/
https://www.ncbi.nlm.nih.gov/pubmed/30623107
http://dx.doi.org/10.1038/s42003-018-0255-8

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