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Prophylactic Cefazolin Dosing and Surgical Site Infections: Does the Dose Matter in Obese Patients?

BACKGROUND: Most surgical prophylaxis guidelines recommend a 3-g cefazolin intravenous dose in patients weighing ≥ 120 kg. However, this recommendation is primarily based on pharmacokinetic studies rather than robust clinical evidence. This study aimed to compare the prevalence of surgical site infe...

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Detalles Bibliográficos
Autores principales: Hussain, Zahid, Curtain, Colin, Mirkazemi, Corinne, Gadd, Karl, Peterson, Gregory M., Zaidi, Syed Tabish R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320352/
https://www.ncbi.nlm.nih.gov/pubmed/30267229
http://dx.doi.org/10.1007/s11695-018-3497-0