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Microglia and amyloid precursor protein coordinate control of transient Candida cerebritis with memory deficits

Bloodborne infections with Candida albicans are an increasingly recognized complication of modern medicine. Here, we present a mouse model of low-grade candidemia to determine the effect of disseminated infection on cerebral function and relevant immune determinants. We show that intravenous injecti...

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Detalles Bibliográficos
Autores principales: Wu, Yifan, Du, Shuqi, Johnson, Jennifer L., Tung, Hui-Ying, Landers, Cameron T., Liu, Yuwei, Seman, Brittany G., Wheeler, Robert T., Costa-Mattioli, Mauro, Kheradmand, Farrah, Zheng, Hui, Corry, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320369/
https://www.ncbi.nlm.nih.gov/pubmed/30610193
http://dx.doi.org/10.1038/s41467-018-07991-4