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Microglia and amyloid precursor protein coordinate control of transient Candida cerebritis with memory deficits
Bloodborne infections with Candida albicans are an increasingly recognized complication of modern medicine. Here, we present a mouse model of low-grade candidemia to determine the effect of disseminated infection on cerebral function and relevant immune determinants. We show that intravenous injecti...
Autores principales: | Wu, Yifan, Du, Shuqi, Johnson, Jennifer L., Tung, Hui-Ying, Landers, Cameron T., Liu, Yuwei, Seman, Brittany G., Wheeler, Robert T., Costa-Mattioli, Mauro, Kheradmand, Farrah, Zheng, Hui, Corry, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320369/ https://www.ncbi.nlm.nih.gov/pubmed/30610193 http://dx.doi.org/10.1038/s41467-018-07991-4 |
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