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AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis

Advanced age and unhealthy dietary habits contribute to the increasing incidence of obesity and type 2 diabetes. These metabolic disorders, which are often accompanied by oxidative stress and compromised nitric oxide (NO) signaling, increase the risk of adverse cardiovascular complications and devel...

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Detalles Bibliográficos
Autores principales: Cordero-Herrera, Isabel, Kozyra, Mikael, Zhuge, Zhengbing, McCann Haworth, Sarah, Moretti, Chiara, Peleli, Maria, Caldeira-Dias, Mayara, Jahandideh, Arghavan, Huirong, Han, Cruz, Josiane de Campos, Kleschyov, Andrei L., Montenegro, Marcelo F., Ingelman-Sundberg, Magnus, Weitzberg, Eddie, Lundberg, Jon O., Carlstrom, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320503/
https://www.ncbi.nlm.nih.gov/pubmed/30559212
http://dx.doi.org/10.1073/pnas.1809406115