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SeqClone: sequential Monte Carlo based inference of tumor subclones

BACKGROUND: Tumor samples are heterogeneous. They consist of varying cell populations or subclones and each subclone is characterized with a distinct single nucleotide variant (SNV) profile. This explains the source of genetic heterogeneity observed in tumor sequencing data. To make precise prognosi...

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Detalles Bibliográficos
Autores principales: Ogundijo, Oyetunji E., Wang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320595/
https://www.ncbi.nlm.nih.gov/pubmed/30611189
http://dx.doi.org/10.1186/s12859-018-2562-y