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SeqClone: sequential Monte Carlo based inference of tumor subclones
BACKGROUND: Tumor samples are heterogeneous. They consist of varying cell populations or subclones and each subclone is characterized with a distinct single nucleotide variant (SNV) profile. This explains the source of genetic heterogeneity observed in tumor sequencing data. To make precise prognosi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320595/ https://www.ncbi.nlm.nih.gov/pubmed/30611189 http://dx.doi.org/10.1186/s12859-018-2562-y |