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Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolic active tissues

BACKGROUND: ATP-binding cassette (ABC) transporters are involved in a huge range of physiological processes. Mutations in the ABCC6 gene cause pseudoxanthoma elasticum, a metabolic disease with progressive soft tissue calcification. METHODS: The aim of the present study was to analyze gene expressio...

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Detalles Bibliográficos
Autores principales: Ibold, Bettina, Faust, Isabel, Tiemann, Janina, Gorgels, Theo G. M. F., Bergen, Arthur A. B., Knabbe, Cornelius, Hendig, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320597/
https://www.ncbi.nlm.nih.gov/pubmed/30611276
http://dx.doi.org/10.1186/s12944-018-0943-x