Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies. Neovascularization during tumorigenesis supplies oxygen and nutrients to proliferative tumor cells, and serves as a conduit for migration. Targeting oncogenes involved in angiogenesis is needed to treat org...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yunzhao, Wang, Dandan, Peng, Hao, Chen, Xi, Han, Xueping, Yu, Jie, Wang, Wenjie, Liang, Lirong, Liu, Zheng, Zheng, Yi, Hu, Jianming, Yang, Lan, Li, Jun, Zhou, Hong, Cui, Xiaobin, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320601/
https://www.ncbi.nlm.nih.gov/pubmed/30609930
http://dx.doi.org/10.1186/s12943-018-0930-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320601/
https://www.ncbi.nlm.nih.gov/pubmed/30609930
http://dx.doi.org/10.1186/s12943-018-0930-x

Ejemplares similares