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Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies. Neovascularization during tumorigenesis supplies oxygen and nutrients to proliferative tumor cells, and serves as a conduit for migration. Targeting oncogenes involved in angiogenesis is needed to treat org...

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Detalles Bibliográficos
Autores principales:	Chen, Yunzhao, Wang, Dandan, Peng, Hao, Chen, Xi, Han, Xueping, Yu, Jie, Wang, Wenjie, Liang, Lirong, Liu, Zheng, Zheng, Yi, Hu, Jianming, Yang, Lan, Li, Jun, Zhou, Hong, Cui, Xiaobin, Li, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320601/ https://www.ncbi.nlm.nih.gov/pubmed/30609930 http://dx.doi.org/10.1186/s12943-018-0930-x

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