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Cucurbitacin B Inhibits the Hippo-YAP Signaling Pathway and Exerts Anticancer Activity in Colorectal Cancer Cells

BACKGROUND: Colorectal carcinoma (CRC) is one of the most frequently diagnosed malignancies. Cucurbitacin B (CuB) is a natural compound isolated from herbs and shows anticancer activity in several cancers. MATERIAL/METHODS: Here, we analyzed the effects of different CuB concentrations on the prolife...

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Detalles Bibliográficos
Autores principales: Chai, Yanting, Xiang, Ke, Wu, Yezi, Zhang, Te, Liu, Ying, Liu, Xuewen, Zhen, Weiguo, Si, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320653/
https://www.ncbi.nlm.nih.gov/pubmed/30566960
http://dx.doi.org/10.12659/MSM.911594