Transcription shapes DNA replication initiation and termination in human cells

Although DNA replication is a fundamental aspect of biology, it is not known what determines where DNA replication starts and stops in the human genome. Here we directly identify and quantitatively compare sites of replication initiation and termination in untransformed human cells. We report that r...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Hung, Keegan, Sarah, Kahli, Malik, Tonzi, Peter, Fenyö, David, Huang, Tony T., Smith, Duncan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320713/
https://www.ncbi.nlm.nih.gov/pubmed/30598550
http://dx.doi.org/10.1038/s41594-018-0171-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320713/
https://www.ncbi.nlm.nih.gov/pubmed/30598550
http://dx.doi.org/10.1038/s41594-018-0171-0

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