Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort

Breast cancer patients with BRCA1/2‐driven tumors may benefit from targeted therapy. It is not clear whether current BRCA screening guidelines are effective at identifying these patients. The purpose of our study was to evaluate the prevalence of inherited BRCA1/2 pathogenic variants in a large, cli...

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Detalles Bibliográficos
Autores principales: Li, Jingmei, Wen, Wei Xiong, Eklund, Martin, Kvist, Anders, Eriksson, Mikael, Christensen, Helene Nordahl, Torstensson, Astrid, Bajalica‐Lagercrantz, Svetlana, Dunning, Alison M., Decker, Brennan, Allen, Jamie, Luccarini, Craig, Pooley, Karen, Simard, Jacques, Dorling, Leila, Easton, Douglas F., Teo, Soo‐Hwang, Hall, Per, Borg, Åke, Grönberg, Henrik, Czene, Kamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Cancer Therapy and Prevention
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320715/
https://www.ncbi.nlm.nih.gov/pubmed/30175445
http://dx.doi.org/10.1002/ijc.31841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320715/
https://www.ncbi.nlm.nih.gov/pubmed/30175445
http://dx.doi.org/10.1002/ijc.31841

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