On the formation of seven-membered rings by arene-ynamide cyclization

ABSTRACT: A Brønsted acid-catalyzed selective arene-ynamide cyclization is described. This reaction proceeds via a keteniminium intermediate and enables the preparation of seven-membered ring enamide products. Mechanistic studies uncover an unusual product inhibition behavior. GRAPHICAL ABSTRACT: [I...

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Detalles Bibliográficos
Autores principales: Brutiu, Bogdan R., Bubeneck, Wilhelm Andrei, Cvetkovic, Olivera, Li, Jing, Maulide, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320749/
https://www.ncbi.nlm.nih.gov/pubmed/30662090
http://dx.doi.org/10.1007/s00706-018-2320-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320749/
https://www.ncbi.nlm.nih.gov/pubmed/30662090
http://dx.doi.org/10.1007/s00706-018-2320-x

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