Oligoclonal T Cells Transiently Expand and Express Tim-3 and PD-1 Following Anti-CD19 CAR T Cell Therapy: A Case Report

Clinical trials of chimeric antigen receptor (CAR) T cells in hematologic malignancy associate remissions with two profiles of CAR T cell proliferation kinetics, which differ based upon costimulatory domain. Additional T cell intrinsic factors that influence or predict clinical response remain uncle...

Descripción completa

Detalles Bibliográficos
Autores principales: Funk, Christopher Ronald, Petersen, Christopher T., Jagirdar, Neera, Ravindranathan, Sruthi, Jaye, David L., Flowers, Christopher R., Langston, Amelia, Waller, Edmund K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320786/
https://www.ncbi.nlm.nih.gov/pubmed/30572564
http://dx.doi.org/10.3390/ijms19124118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320786/
https://www.ncbi.nlm.nih.gov/pubmed/30572564
http://dx.doi.org/10.3390/ijms19124118

Ejemplares similares