Cargando…

FKBP8 Enhances Protein Stability of the CLC-1 Chloride Channel at the Plasma Membrane

Mutations in the skeletal muscle-specific CLC-1 chloride channel are associated with the human hereditary disease myotonia congenita. The molecular pathophysiology underlying some of the disease-causing mutations can be ascribed to defective human CLC-1 protein biosynthesis. CLC-1 protein folding is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peng, Yi-Jheng, Lee, Yi-Ching, Fu, Ssu-Ju, Chien, Yun-Chia, Liao, Yi-Fan, Chen, Tsung-Yu, Jeng, Chung-Jiuan, Tang, Chih-Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320802/ https://www.ncbi.nlm.nih.gov/pubmed/30487393 http://dx.doi.org/10.3390/ijms19123783

Ejemplares similares

Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β
por: Peng, Yi-Jheng, et al.
Publicado: (2016)

Defective Gating and Proteostasis of Human ClC-1 Chloride Channel: Molecular Pathophysiology of Myotonia Congenita
por: Jeng, Chung-Jiuan, et al.
Publicado: (2020)

CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy
por: Fu, Ssu-Ju, et al.
Publicado: (2020)

Regulation of ClC-2 Chloride Channel Proteostasis by Molecular Chaperones: Correction of Leukodystrophy-Associated Defect
por: Fu, Ssu-Ju, et al.
Publicado: (2021)

The Cullin 4A/B-DDB1-Cereblon E3 Ubiquitin Ligase Complex Mediates the Degradation of CLC-1 Chloride Channels
por: Chen, Yi-An, et al.
Publicado: (2015)

Myotonia Congenita Mutation Enhances the Degradation of Human CLC-1 Chloride Channels
por: Lee, Ting-Ting, et al.
Publicado: (2013)

Physiology and Pathophysiology of CLC-1: Mechanisms of a Chloride Channel Disease, Myotonia
por: Tang, Chih-Yung, et al.
Publicado: (2011)

Cysteine Modification of a Putative Pore Residue in Clc-0: Implication for the Pore Stoichiometry of Clc Chloride Channels
por: Lin, Chia-Wei, et al.
Publicado: (2000)

Electrostatic Control and Chloride Regulation of the Fast Gating of ClC-0 Chloride Channels
por: Chen, Tsung-Yu, et al.
Publicado: (2003)

ClC chloride channels
por: Mindell, Joe, et al.
Publicado: (2001)

Elimination of the Slow Gating of Clc-0 Chloride Channel by a Point Mutation
por: Lin, Yu-Wen, et al.
Publicado: (1999)

Structure of the human ClC-1 chloride channel
por: Wang, Kaituo, et al.
Publicado: (2019)

GlialCAM, a CLC-2 Cl(-) Channel Subunit, Activates the Slow Gate of CLC Chloride Channels
por: Jeworutzki, Elena, et al.
Publicado: (2014)

Extracellular Zinc Ion Inhibits ClC-0 Chloride Channels by Facilitating Slow Gating
por: Chen, Tsung-Yu
Publicado: (1998)

ClC-3 chloride channel in hippocampal neuronal apoptosis
por: Xu, Lijuan, et al.
Publicado: (2013)

Structure of the CLC-1 chloride channel from Homo sapiens
por: Park, Eunyong, et al.
Publicado: (2018)

Electro-steric opening of the clc-2 chloride channel gate
por: De Jesús-Pérez, José J., et al.
Publicado: (2021)

Side-chain Charge Effects and Conductance Determinants in the Pore of ClC-0 Chloride Channels
por: Chen, Mei-Fang, et al.
Publicado: (2003)

Different Fast-Gate Regulation by External Cl(−) and H(+) of the Muscle-Type Clc Chloride Channels
por: Chen, Mei-Fang, et al.
Publicado: (2001)

ClC1 chloride channel in myotonic dystrophy type 2 and ClC1 splicing in vitro
por: URSU, SIMONA-FELICIA, et al.
Publicado: (2012)

Proton-dependent inhibition, inverted voltage activation, and slow gating of CLC-0 Chloride Channel
por: Kwon, Hwoi Chan, et al.
Publicado: (2020)

Fast and Slow Gating Relaxations in the Muscle Chloride Channel Clc-1
por: Accardi, Alessio, et al.
Publicado: (2000)

Molecular Pharmacology of Kidney and Inner Ear CLC-K Chloride Channels
por: Gradogna, Antonella, et al.
Publicado: (2010)

Gating the glutamate gate of CLC-2 chloride channel by pore occupancy
por: De Jesús-Pérez, José J., et al.
Publicado: (2016)

Structure of a CLC chloride ion channel by cryo-electron microscopy
por: Park, Eunyong, et al.
Publicado: (2016)

Chloride Channelopathies of ClC-2
por: Bi, Miao Miao, et al.
Publicado: (2013)

The ClC-0 chloride channel is a ‘broken’ Cl(−)/H(+) antiporter
por: Lísal, Jiří, et al.
Publicado: (2008)

The Muscle Chloride Channel ClC-1 Is Not Directly Regulated by Intracellular ATP
por: Zifarelli, Giovanni, et al.
Publicado: (2008)

ClC-1 chloride channels: state-of-the-art research and future challenges
por: Imbrici, Paola, et al.
Publicado: (2015)

Role of PKC in the Regulation of the Human Kidney Chloride Channel ClC-Ka
por: Gerbino, Andrea, et al.
Publicado: (2020)

Identification of MKRN1 as a second E3 ligase for Eag1 potassium channels reveals regulation via differential degradation
por: Fang, Ya-Ching, et al.
Publicado: (2021)

Overexpression of chloride channel-3 (ClC-3) is associated with human cervical carcinoma development and prognosis
por: Guan, Yu-tao, et al.
Publicado: (2019)

Permeation and Block of the Skeletal Muscle Chloride Channel, ClC-1, by Foreign Anions
por: Rychkov, G.Y., et al.
Publicado: (1998)

Temperature Dependence of Fast and Slow Gating Relaxations of ClC-0 Chloride Channels
por: Pusch, Michael, et al.
Publicado: (1997)

Impaired Wheel Running Exercise in CLC-1 Chloride Channel-Deficient Myotonic Mice
por: van Lunteren, Erik, et al.
Publicado: (2011)

Regulation of Fast-Spiking Basket Cell Synapses by the Chloride Channel ClC–2
por: Földy, Csaba, et al.
Publicado: (2010)

Dissecting a regulatory calcium-binding site of CLC-K kidney chloride channels
por: Gradogna, Antonella, et al.
Publicado: (2012)

Gluconate suppresses seizure activity in developing brains by inhibiting CLC-3 chloride channels
por: Wu, Zheng, et al.
Publicado: (2019)

ClC Channels and Transporters: Structure, Physiological Functions, and Implications in Human Chloride Channelopathies
por: Poroca, Diogo R., et al.
Publicado: (2017)

FKBP51 mediates resilience to inflammation-induced anxiety through regulation of glutamic acid decarboxylase 65 expression in mouse hippocampus
por: Gan, Yu-Ling, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8m23g109f2h2ionbsamn64v7fd