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Microparticles Carrying Sonic Hedgehog Are Increased in Humans with Peripheral Artery Disease

Sonic hedgehog (Shh) is a prototypical angiogenic agent with a crucial role in the regulation of angiogenesis. Experimental studies have shown that Shh is upregulated in response to ischemia. Also, Shh may be found on the surface of circulating microparticles (MPs) and MPs bearing Shh (Shh + MPs) ha...

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Detalles Bibliográficos
Autores principales: Giarretta, Igor, Gatto, Ilaria, Marcantoni, Margherita, Lupi, Giulia, Tonello, Diego, Gaetani, Eleonora, Pitocco, Dario, Iezzi, Roberto, Truma, Addolorata, Porfidia, Angelo, Visonà, Adriana, Tondi, Paolo, Pola, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320804/
https://www.ncbi.nlm.nih.gov/pubmed/30544841
http://dx.doi.org/10.3390/ijms19123954