Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls

By catalyzing the hydrolysis of sphingomyelin into ceramide, acid sphingomyelinase (ASM) changes the local composition of the plasma membrane with effects on receptor-mediated signaling. Altered enzyme activities have been noted in common human diseases, including alcohol dependence. However, the un...

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Detalles Bibliográficos
Autores principales: Mühle, Christiane, Weinland, Christian, Gulbins, Erich, Lenz, Bernd, Kornhuber, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320816/
https://www.ncbi.nlm.nih.gov/pubmed/30551571
http://dx.doi.org/10.3390/ijms19124028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320816/
https://www.ncbi.nlm.nih.gov/pubmed/30551571
http://dx.doi.org/10.3390/ijms19124028

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