Enantioselective Michael Addition of Aldehydes to Maleimides Organocatalyzed by a Chiral Primary Amine-Salicylamide

A primary amine-salicylamide derived from chiral trans-cyclohexane-1,2-diamine was used as an organocatalyst for the enantioselective conjugate addition of aldehydes, mainly α,α-disubstituted to N-substituted maleimides. The reaction was performed in toluene as a solvent at room temperature. The cor...

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Detalles Bibliográficos
Autores principales: Torregrosa-Chinillach, Alejandro, Moragues, Adrien, Pérez-Furundarena, Haritz, Chinchilla, Rafael, Gómez-Bengoa, Enrique, Guillena, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320823/
https://www.ncbi.nlm.nih.gov/pubmed/30545145
http://dx.doi.org/10.3390/molecules23123299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320823/
https://www.ncbi.nlm.nih.gov/pubmed/30545145
http://dx.doi.org/10.3390/molecules23123299

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