N-(2-Hydroxy)-propyl-3-trimethylammonium, O-Mysristoyl Chitosan Enhances the Solubility and Intestinal Permeability of Anticancer Curcumin

An amphiphilic derivative of chitosan containing quaternary ammonium and myristoyl groups, herein named as ammonium myristoyl chitosan (DMCat), was synthesized by reacting glycidyltrimethylammonium chloride (GTMAC) and myristoyl chitosan (DMCh). The success of the modification was confirmed using Fo...

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Detalles Bibliográficos
Autores principales: Silva, Daniella S., M. dos Santos, Danilo, Almeida, Andreia, Marchiori, Leonardo, Campana-Filho, Sérgio P., Ribeiro, Sidney J. L., Sarmento, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320830/
https://www.ncbi.nlm.nih.gov/pubmed/30463361
http://dx.doi.org/10.3390/pharmaceutics10040245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320830/
https://www.ncbi.nlm.nih.gov/pubmed/30463361
http://dx.doi.org/10.3390/pharmaceutics10040245

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