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N-(2-Hydroxy)-propyl-3-trimethylammonium, O-Mysristoyl Chitosan Enhances the Solubility and Intestinal Permeability of Anticancer Curcumin
An amphiphilic derivative of chitosan containing quaternary ammonium and myristoyl groups, herein named as ammonium myristoyl chitosan (DMCat), was synthesized by reacting glycidyltrimethylammonium chloride (GTMAC) and myristoyl chitosan (DMCh). The success of the modification was confirmed using Fo...
Autores principales: | Silva, Daniella S., M. dos Santos, Danilo, Almeida, Andreia, Marchiori, Leonardo, Campana-Filho, Sérgio P., Ribeiro, Sidney J. L., Sarmento, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320830/ https://www.ncbi.nlm.nih.gov/pubmed/30463361 http://dx.doi.org/10.3390/pharmaceutics10040245 |
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