Combining a QSAR Approach and Structural Analysis to Derive an SAR Map of Lyn Kinase Inhibition

Lyn kinase, a member of the Src family of protein tyrosine kinases, is mainly expressed by various hematopoietic cells, neural and adipose tissues. Abnormal Lyn kinase regulation causes various diseases such as cancers. Thus, Lyn represents, a potential target to develop new antitumor drugs. In the...

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Detalles Bibliográficos
Autores principales: Naboulsi, Imane, Aboulmouhajir, Aziz, Kouisni, Lamfeddal, Bekkaoui, Faouzi, Yasri, Abdelaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320833/
https://www.ncbi.nlm.nih.gov/pubmed/30544914
http://dx.doi.org/10.3390/molecules23123271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320833/
https://www.ncbi.nlm.nih.gov/pubmed/30544914
http://dx.doi.org/10.3390/molecules23123271

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