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Combining a QSAR Approach and Structural Analysis to Derive an SAR Map of Lyn Kinase Inhibition
Lyn kinase, a member of the Src family of protein tyrosine kinases, is mainly expressed by various hematopoietic cells, neural and adipose tissues. Abnormal Lyn kinase regulation causes various diseases such as cancers. Thus, Lyn represents, a potential target to develop new antitumor drugs. In the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320833/ https://www.ncbi.nlm.nih.gov/pubmed/30544914 http://dx.doi.org/10.3390/molecules23123271 |