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Investigation of Combined Cyclodextrin and Hydrogel Formulation for Ocular Delivery of Dexamethasone Acetate by Means of Experimental Designs

Dexamethasone acetate (DXMa) has proven its efficiency to treat corneal inflammation, without a great propensity to increase intraocular pressure. Unfortunately, its poor aqueous solubility, associated with a rapid precorneal elimination, results in a low drug bioavailability and a low penetration a...

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Detalles Bibliográficos
Autores principales: Mazet, Roseline, Choisnard, Luc, Levilly, Delphine, Wouessidjewe, Denis, Gèze, Annabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320851/
https://www.ncbi.nlm.nih.gov/pubmed/30513707
http://dx.doi.org/10.3390/pharmaceutics10040249