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Investigation of Combined Cyclodextrin and Hydrogel Formulation for Ocular Delivery of Dexamethasone Acetate by Means of Experimental Designs
Dexamethasone acetate (DXMa) has proven its efficiency to treat corneal inflammation, without a great propensity to increase intraocular pressure. Unfortunately, its poor aqueous solubility, associated with a rapid precorneal elimination, results in a low drug bioavailability and a low penetration a...
Autores principales: | Mazet, Roseline, Choisnard, Luc, Levilly, Delphine, Wouessidjewe, Denis, Gèze, Annabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320851/ https://www.ncbi.nlm.nih.gov/pubmed/30513707 http://dx.doi.org/10.3390/pharmaceutics10040249 |
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