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Preparation and Characterization of Spherical Amorphous Solid Dispersion with Amphotericin B
In the present study, new polymer microspheres of amphotericin B (AmB) were prepared by a spray drying technique using cyclodextrin polymers (Poly-CD) to improve the solubility and dissolution of AmB, to prevent in vivo toxic AmB aggregations. Formulations were characterized through scanning electro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320868/ https://www.ncbi.nlm.nih.gov/pubmed/30453493 http://dx.doi.org/10.3390/pharmaceutics10040235 |