Bioactivity-Guided Separation of Potential D(2) Dopamine Receptor Antagonists from Aurantii Fructus based on Molecular Docking Combined with High-Speed Counter-Current Chromatography

The typical compounds of Aurantii fructus (AF) reported in previous research were screened for their high antagonistic ability on the D(2) dopamine receptor (D(2)R) in silico, and then bioactivity-guided separation was undertaken on the potential D(2)R antagonists from AF using high-speed counter-cu...

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Detalles Bibliográficos
Autores principales: He, Yingjie, Zhu, Shihao, Wu, Changqiao, Lu, Ying, Tang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320876/
https://www.ncbi.nlm.nih.gov/pubmed/30501090
http://dx.doi.org/10.3390/molecules23123135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320876/
https://www.ncbi.nlm.nih.gov/pubmed/30501090
http://dx.doi.org/10.3390/molecules23123135

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