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Aminoribosylated Analogues of Muraymycin Nucleoside Antibiotics

Nucleoside antibiotics are uridine-derived natural products that inhibit the bacterial membrane protein MraY. MraY is a key enzyme in the membrane-associated intracellular stages of peptidoglycan biosynthesis and therefore considered to be a promising, yet unexploited target for novel antibacterial...

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Detalles Bibliográficos
Autores principales: Wiegmann, Daniel, Koppermann, Stefan, Ducho, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320880/
https://www.ncbi.nlm.nih.gov/pubmed/30486316
http://dx.doi.org/10.3390/molecules23123085