Cargando…

Aminoribosylated Analogues of Muraymycin Nucleoside Antibiotics

Nucleoside antibiotics are uridine-derived natural products that inhibit the bacterial membrane protein MraY. MraY is a key enzyme in the membrane-associated intracellular stages of peptidoglycan biosynthesis and therefore considered to be a promising, yet unexploited target for novel antibacterial...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wiegmann, Daniel, Koppermann, Stefan, Ducho, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320880/ https://www.ncbi.nlm.nih.gov/pubmed/30486316 http://dx.doi.org/10.3390/molecules23123085

Ejemplares similares

Analogues of Muraymycin Nucleoside Antibiotics with Epimeric Uridine-Derived Core Structures
por: Spork, Anatol P., et al.
Publicado: (2018)

Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit
por: Heib, Anna, et al.
Publicado: (2019)

Muraymycin nucleoside-peptide antibiotics: uridine-derived natural products as lead structures for the development of novel antibacterial agents
por: Wiegmann, Daniel, et al.
Publicado: (2016)

Synthesis of an Antimicrobial Enterobactin‐Muraymycin Conjugate for Improved Activity Against Gram‐Negative Bacteria
por: Rohrbacher, Christian, et al.
Publicado: (2022)

Merging Natural Products: Muraymycin–Sansanmycin Hybrid Structures as Novel Scaffolds for Potential Antibacterial Agents
por: Niro, Giuliana, et al.
Publicado: (2020)

Pyridoxal-5′-Phosphate-Dependent Alkyl Transfer in Nucleoside Antibiotic Biosynthesis
por: Cui, Zheng, et al.
Publicado: (2020)

New MraY(AA) Inhibitors with an Aminoribosyl Uridine Structure and an Oxadiazole
por: Wan, Hongwei, et al.
Publicado: (2022)

Oligonucleotide analogues with cationic backbone linkages
por: Meng, Melissa, et al.
Publicado: (2018)

Theoretical Study of Intermolecular Interactions between Critical Residues of Membrane Protein MraY(AA) and Promising Antibiotic Muraymycin D2
por: Malek Zadeh, Saeid, et al.
Publicado: (2020)

Nucleoside Analogues as Antibacterial Agents
por: Thomson, Jessica M., et al.
Publicado: (2019)

Identification of Mur34 as the Novel Negative Regulator Responsible for the Biosynthesis of Muraymycin in Streptomyces sp. NRRL30471
por: Xu, Dongmei, et al.
Publicado: (2013)

Nucleoside analogues for the treatment of coronavirus infections
por: Pruijssers, Andrea J, et al.
Publicado: (2019)

Nucleoside analogues for the treatment of animal trypanosomiasis
por: Mabille, Dorien, et al.
Publicado: (2022)

Advances in antiviral nucleoside analogues and their prodrugs
por: Seley-Radtke, Katherine, et al.
Publicado: (2018)

A Sub-Micromolar MraY(AA) Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling
por: Oliver, Martin, et al.
Publicado: (2022)

Synthesis and photophysical characterization of fluorescent indole nucleoside analogues
por: Sawyer, Jacob M., et al.
Publicado: (2023)

Nucleoside Analogues. Chemistry, Biology, and Medical Applications
por: Levinson, Barry L.
Publicado: (1980)

Broad-Spectrum Antiviral Strategies and Nucleoside Analogues
por: Geraghty, Robert J., et al.
Publicado: (2021)

Analogues of Pyrimidine Nucleosides as Mycobacteria Growth Inhibitors
por: Alexandrova, Liudmila A., et al.
Publicado: (2022)

Flex-nucleoside analogues – Novel therapeutics against filoviruses
por: Yates, Mary K., et al.
Publicado: (2017)

Synthesis of some novel hydrazono acyclic nucleoside analogues
por: Soltani Rad, Mohammad N, et al.
Publicado: (2010)

Synthesis of ribavirin 2’-Me-C-nucleoside analogues
por: Cosson, Fanny, et al.
Publicado: (2017)

N,O‐Nucleoside Analogues: Metabolic and Apoptotic Activity
por: Marraffa, Andrea, et al.
Publicado: (2020)

Photochemical Synthesis of Nucleoside Analogues from Cyclobutanones: Bicyclic and Isonucleosides
por: Jaffer, Mileina, et al.
Publicado: (2010)

Synthesis of New Imidazopyridine Nucleoside Derivatives Designed as Maribavir Analogues
por: Papadakis, Georgios, et al.
Publicado: (2020)

Investigation of 5’-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents
por: Khandazhinskaya, Anastasia L., et al.
Publicado: (2019)

Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis
por: Sumabe, Balagra Kasim, et al.
Publicado: (2021)

In vitro and in vivo antiplasmodial evaluation of sugar-modified nucleoside analogues
por: Bege, Miklós, et al.
Publicado: (2023)

Novel acyclic nucleoside analogues as inhibitors of HIV-1 RT
por: Singh, Anuradha, et al.
Publicado: (2012)

Recent Advances in the Chemical Synthesis and Evaluation of Anticancer Nucleoside Analogues
por: Guinan, Mieke, et al.
Publicado: (2020)

Synthetic strategies toward 1,3-oxathiolane nucleoside analogues
por: Aher, Umesh P, et al.
Publicado: (2021)

Structure-based design of nucleoside-derived analogues as sulfotransferase inhibitors
por: Kershaw, Neil M., et al.
Publicado: (2019)

Microwave-assisted organic synthesis of nucleoside ProTide analogues
por: Bordoni, Cinzia, et al.
Publicado: (2019)

Single-molecule fluorescence detection of a tricyclic nucleoside analogue
por: Samaan, George N., et al.
Publicado: (2020)

The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold
por: Yates, Mary K., et al.
Publicado: (2019)

Cladribine Analogues via O(6)-(Benzotriazolyl) Derivatives of Guanine Nucleosides
por: Satishkumar, Sakilam, et al.
Publicado: (2015)

Non-Nucleosidic Analogues of Polyaminonucleosides and Their Influence on Thermodynamic Properties of Derived Oligonucleotides
por: Brzezinska, Jolanta, et al.
Publicado: (2015)

Novel Nucleoside Analogues as Effective Antiviral Agents for Zika Virus Infections
por: Bassetto, Marcella, et al.
Publicado: (2020)

Targeting SARS-CoV-2 Polymerase with New Nucleoside Analogues
por: Daikopoulou, Vasiliki, et al.
Publicado: (2021)

Mitochondrial toxicities of nucleoside analogue reverse transcriptase inhibitors in AIDS cases
por: Marfatia, Yogesh S., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3acn2k71leeq12qgvb5125c933