Characterization and Antiproliferative Activity of a Novel 2-Aminothiophene Derivative-β-Cyclodextrin Binary System

The novel 2-aminothiophene derivative 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (6CN) has shown potential anti-proliferative activity in human cancer cell lines. However, the poor aqueous solubility of 6CN impairs its clinical use. This work aimed to develop binary 6CN-β-cyclodextri...

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Detalles Bibliográficos
Autores principales: Ferreira, Elayne Barros, da Silva Júnior, Walter Ferreira, de Oliveira Pinheiro, Jonas Gabriel, da Fonseca, Aldilane Gonçalves, Moura Lemos, Telma Maria Araújo, de Oliveira Rocha, Hugo Alexandre, de Azevedo, Eduardo Pereira, Mendonça Junior, Francisco Jaime Bezerra, Neves de Lima, Ádley Antonini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320897/
https://www.ncbi.nlm.nih.gov/pubmed/30501061
http://dx.doi.org/10.3390/molecules23123130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320897/
https://www.ncbi.nlm.nih.gov/pubmed/30501061
http://dx.doi.org/10.3390/molecules23123130

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