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Characterization and Antiproliferative Activity of a Novel 2-Aminothiophene Derivative-β-Cyclodextrin Binary System
The novel 2-aminothiophene derivative 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (6CN) has shown potential anti-proliferative activity in human cancer cell lines. However, the poor aqueous solubility of 6CN impairs its clinical use. This work aimed to develop binary 6CN-β-cyclodextri...
Autores principales: | Ferreira, Elayne Barros, da Silva Júnior, Walter Ferreira, de Oliveira Pinheiro, Jonas Gabriel, da Fonseca, Aldilane Gonçalves, Moura Lemos, Telma Maria Araújo, de Oliveira Rocha, Hugo Alexandre, de Azevedo, Eduardo Pereira, Mendonça Junior, Francisco Jaime Bezerra, Neves de Lima, Ádley Antonini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320897/ https://www.ncbi.nlm.nih.gov/pubmed/30501061 http://dx.doi.org/10.3390/molecules23123130 |
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