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An Evaluation of the Potential of NMR Spectroscopy and Computational Modelling Methods to Inform Biopharmaceutical Formulations

Protein-based therapeutics are considered to be one of the most important classes of pharmaceuticals on the market. The growing need to prolong stability of high protein concentrations in liquid form has proven to be challenging. Therefore, significant effort is being made to design formulations whi...

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Detalles Bibliográficos
Autores principales: Pandya, Akash, Howard, Mark J., Zloh, Mire, Dalby, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320905/
https://www.ncbi.nlm.nih.gov/pubmed/30248922
http://dx.doi.org/10.3390/pharmaceutics10040165