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Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification

Receptors for gonadotropin releasing hormone (GnRH) are highly expressed in various human cancers including breast, ovarian, endometrial, prostate and colorectal cancer. Ligands like human GnRH-I or the sea lamprey analogue GnRH-III represent a promising approach for the development of efficient dru...

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Detalles Bibliográficos
Autores principales: Schuster, Sabine, Biri-Kovács, Beáta, Szeder, Bálint, Buday, László, Gardi, János, Szabó, Zsuzsanna, Halmos, Gábor, Mező, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320914/
https://www.ncbi.nlm.nih.gov/pubmed/30423956
http://dx.doi.org/10.3390/pharmaceutics10040223