Altered Purinergic Receptor Sensitivity in Type 2 Diabetes-Associated Endothelial Dysfunction and Up(4)A-Mediated Vascular Contraction

Purinergic signaling may be altered in diabetes accounting for endothelial dysfunction. Uridine adenosine tetraphosphate (Up(4)A), a novel dinucleotide substance, regulates vascular function via both purinergic P1 and P2 receptors (PR). Up(4)A enhances vascular contraction in isolated arteries of di...

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Detalles Bibliográficos
Autores principales: Mahdi, Ali, Jiao, Tong, Tratsiakovich, Yahor, Yang, Jiangning, Östenson, Claes-Göran, Pernow, John, Zhou, Zhichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320923/
https://www.ncbi.nlm.nih.gov/pubmed/30544633
http://dx.doi.org/10.3390/ijms19123942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320923/
https://www.ncbi.nlm.nih.gov/pubmed/30544633
http://dx.doi.org/10.3390/ijms19123942

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