A Ruthenium(II) N-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 MAPK Pathway

The p38 MAPK pathway is known to influence the anti-tumor effects of several chemotherapeutics, including that of organometallic drugs. Previous studies have demonstrated the important role of p38 both as a regulator and a sensor of cellular reactive oxygen species (ROS) levels. Investigating the an...

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Detalles Bibliográficos
Autores principales: Dabiri, Yasamin, Schmid, Alice, Theobald, Jannick, Blagojevic, Biljana, Streciwilk, Wojciech, Ott, Ingo, Wölfl, Stefan, Cheng, Xinlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320930/
https://www.ncbi.nlm.nih.gov/pubmed/30544880
http://dx.doi.org/10.3390/ijms19123964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320930/
https://www.ncbi.nlm.nih.gov/pubmed/30544880
http://dx.doi.org/10.3390/ijms19123964

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