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A Ruthenium(II) N-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 MAPK Pathway

The p38 MAPK pathway is known to influence the anti-tumor effects of several chemotherapeutics, including that of organometallic drugs. Previous studies have demonstrated the important role of p38 both as a regulator and a sensor of cellular reactive oxygen species (ROS) levels. Investigating the an...

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Detalles Bibliográficos
Autores principales:	Dabiri, Yasamin, Schmid, Alice, Theobald, Jannick, Blagojevic, Biljana, Streciwilk, Wojciech, Ott, Ingo, Wölfl, Stefan, Cheng, Xinlai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320930/ https://www.ncbi.nlm.nih.gov/pubmed/30544880 http://dx.doi.org/10.3390/ijms19123964

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