Reprogramming Tumor Associated Macrophage Phenotype by a Polysaccharide from Ilex asprella for Sarcoma Immunotherapy

We report here the discovery of an acidic polysaccharide, namely IAPS-2, from the root of Ilex asprella, with anti-tumor activity via a repolarizing tumor associated macrophages (TAMs) phenotype. We obtained IAPS-2 polysaccharide from this herb based on acidity and found that IAPS-2 expressed the ac...

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Detalles Bibliográficos
Autores principales: Li, Qiu, Hao, Zhihui, Hong, Yeting, He, Wei, Zhao, Wenwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320939/
https://www.ncbi.nlm.nih.gov/pubmed/30513582
http://dx.doi.org/10.3390/ijms19123816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320939/
https://www.ncbi.nlm.nih.gov/pubmed/30513582
http://dx.doi.org/10.3390/ijms19123816

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