Synthesis and Evaluation of 3-Substituted-4-(quinoxalin-6-yl) Pyrazoles as TGF-β Type I Receptor Kinase Inhibitors

The transforming growth factor-β (TGF-β), in which overexpression has been associated with various diseases, has become an attractive molecular target for the treatment of cancers. Thirty-two quinoxaline-derivatives of 3-substituted-4-(quinoxalin-6-yl) pyrazoles 14a–d, 15a–d, 16a–d, 17a–d, 18a–d, 19...

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Detalles Bibliográficos
Autores principales: Zhao, Li-Min, Guo, Zhen, Xue, Yi-Jie, Min, Jun Zhe, Zhu, Wen-Jing, Li, Xiang-Yu, Piao, Hu-Ri, Jin, Cheng Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320941/
https://www.ncbi.nlm.nih.gov/pubmed/30572609
http://dx.doi.org/10.3390/molecules23123369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320941/
https://www.ncbi.nlm.nih.gov/pubmed/30572609
http://dx.doi.org/10.3390/molecules23123369

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