Mepazine Inhibits RANK-Induced Osteoclastogenesis Independent of Its MALT1 Inhibitory Function

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is an intracellular cysteine protease (paracaspase) that plays an integral role in innate and adaptive immunity. The phenothiazine mepazine has been shown to inhibit the proteolytic activity of MALT1 and is frequently used to...

Descripción completa

Detalles Bibliográficos
Autores principales: Meloni, Laura, Verstrepen, Lynn, Kreike, Marja, Staal, Jens, Driege, Yasmine, Afonina, Inna S., Beyaert, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320945/
https://www.ncbi.nlm.nih.gov/pubmed/30513612
http://dx.doi.org/10.3390/molecules23123144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320945/
https://www.ncbi.nlm.nih.gov/pubmed/30513612
http://dx.doi.org/10.3390/molecules23123144

Ejemplares similares