Probing the Action of Permeation Enhancers Sodium Cholate and N-dodecyl-β-D-maltoside in a Porcine Jejunal Mucosal Explant System

The small intestinal epithelium constitutes a major permeability barrier for the oral administration of therapeutic drugs with poor bioavailability, and permeation enhancers (PEs) are required to increase the paracellular and/or transcellular uptake of such drugs. Many PEs act as surfactants by pert...

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Detalles Bibliográficos
Autores principales: Danielsen, E. Michael, Hansen, Gert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320951/
https://www.ncbi.nlm.nih.gov/pubmed/30279382
http://dx.doi.org/10.3390/pharmaceutics10040172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320951/
https://www.ncbi.nlm.nih.gov/pubmed/30279382
http://dx.doi.org/10.3390/pharmaceutics10040172

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