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Galactosylated Chitosan-Functionalized Mesoporous Silica Nanoparticle Loading by Calcium Leucovorin for Colon Cancer Cell-Targeted Drug Delivery

Targeted drug delivery to colon cancer cells can significantly improve the efficiency of treatment. We firstly synthesized carboxyl-modified mesoporous silica nanoparticles (MSN–COOH) via two-step synthesis, and then developed calcium leucovorin (LV)-loaded carboxyl-modified mesoporous silica nanopa...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Wang, Fan, Zhu, Yongchao, Li, Xue, Liu, Xiaojing, Pang, Jingjing, Pan, Weisan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320954/
https://www.ncbi.nlm.nih.gov/pubmed/30486276
http://dx.doi.org/10.3390/molecules23123082