Synthesis, Experimental and Density Functional Theory (DFT) Studies on Solubility of Camptothecin Derivatives

Two camptothecin derivatives, 10-cyclohexyl-7-methyl-20(S)-camptothecin and 7-methyl-10-morpholino-20(S)-camptothecin, were synthesized and their differences in solubility were investigated using four chosen solvent systems. Based on our results, 10-cyclohexyl-7-methyl-20(S)-camptothecin exhibited h...

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Detalles Bibliográficos
Autores principales: Lai, Chin-Hung, Chang, Chia-Chin, Weng, Yi-Lin, Chuang, Ta-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320962/
https://www.ncbi.nlm.nih.gov/pubmed/30513778
http://dx.doi.org/10.3390/molecules23123170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320962/
https://www.ncbi.nlm.nih.gov/pubmed/30513778
http://dx.doi.org/10.3390/molecules23123170

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