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Synthesis, Experimental and Density Functional Theory (DFT) Studies on Solubility of Camptothecin Derivatives

Two camptothecin derivatives, 10-cyclohexyl-7-methyl-20(S)-camptothecin and 7-methyl-10-morpholino-20(S)-camptothecin, were synthesized and their differences in solubility were investigated using four chosen solvent systems. Based on our results, 10-cyclohexyl-7-methyl-20(S)-camptothecin exhibited h...

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Detalles Bibliográficos
Autores principales:	Lai, Chin-Hung, Chang, Chia-Chin, Weng, Yi-Lin, Chuang, Ta-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320962/ https://www.ncbi.nlm.nih.gov/pubmed/30513778 http://dx.doi.org/10.3390/molecules23123170

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